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Publication : The mouse lysyl oxidase gene (Lox) resides on chromosome 18.

First Author  Chang YS Year  1993
Journal  Cytogenet Cell Genet Volume  63
Issue  1 Pages  47-9
PubMed ID  8095446 Mgi Jnum  J:4535
Mgi Id  MGI:53023 Doi  10.1159/000133500
Citation  Chang YS, et al. (1993) The mouse lysyl oxidase gene (Lox) resides on chromosome 18. Cytogenet Cell Genet 63(1):47-9
abstractText  Lysyl oxidase initiates crosslink formation of the connective tissue matrix. This enzyme can also revert the ras phenotype in mouse NIH 3T3-transformed cells. Even though lysyl oxidase may participate in many different biological processes, its chromosomal assignment in the mouse genome remains to be addressed. Southern analysis of a panel of Chinese hamster x mouse somatic cell hybrids was utilized to assign the lysyl oxidase gene (Lox) to mouse Chromosome 18.
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