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Publication : The human gene for the zona pellucida glycoprotein ZP3 and a second polymorphic locus are located on chromosome 7.

First Author  van Duin M Year  1993
Journal  Cytogenet Cell Genet Volume  63
Issue  2 Pages  111-3
PubMed ID  8467708 Mgi Jnum  J:4671
Mgi Id  MGI:53154 Doi  10.1159/000133512
Citation  van Duin M, et al. (1993) The human gene for the zona pellucida glycoprotein ZP3 and a second polymorphic locus are located on chromosome 7. Cytogenet Cell Genet 63(2):111-3
abstractText  Southern blot analysis of genomic DNA and gene-cloning experiments have recently shown that the human ZP3 gene is not a single-copy gene. The human genome harbors sequences encoding a protein of 424 amino acids and, in addition, a polymorphic locus with the potential to give rise to a probably nonfunctional polypeptide of 372 residues. In this report it is shown, by screening of a panel of human x hamster hybrid cell lines, that both the ZP3 and ZP3P loci are located on human chromosome 7.
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