| First Author | van Es HH | Year | 1993 |
| Journal | Cytogenet Cell Genet | Volume | 63 |
| Issue | 2 | Pages | 114-6 |
| PubMed ID | 8467709 | Mgi Jnum | J:4670 |
| Mgi Id | MGI:53153 | Doi | 10.1159/000133513 |
| Citation | van Es HH, et al. (1993) Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37. Cytogenet Cell Genet 63(2):114-6 |
| abstractText | UDP glucuronosyltransferases (UGTs) comprise a multigene family of drug-metabolizing enzymes. The sub-family of UGTs that conjugate bilirubin and phenolic compounds with glucuronic acid has been termed UGT1A1. In man, UGT1A1 isoforms are encoded by a single gene, UGT1A1. Protein isoforms encoded by UGT1A1 originate by alternative splicing. In the present study, we used the cDNA of UGT1A1*4, a bilirubin-conjugating isoform, to localize the UGT1A1 locus in the human genome. The UGT1A1 gene was assigned by in situ hybridization to chromosome region 2q37. |
