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Publication : The mouse iduronate sulfatase gene: identification of a novel transcript.

First Author  Daniele A Year  1993
Journal  Biochem Biophys Res Commun Volume  194
Issue  3 Pages  1030-7
PubMed ID  8352760 Mgi Jnum  J:14030
Mgi Id  MGI:62207 Doi  10.1006/bbrc.1993.1925
Citation  Daniele A, et al. (1993) The mouse iduronate sulfatase gene: identification of a novel transcript. Biochem Biophys Res Commun 194(3):1030-7
abstractText  Complementary DNAs, cDNAs, coding for iduronate sulfatase (IDS, E.C.3.1.6.13) have been isolated and characterized in man and mouse. The murine cDNA (MTA16) was highly homologous to the human counterpart. By screening the same mouse thymus cDNA library another cDNA (MTA13) was isolated: it is 1831 bp long and is identical to a part of the MTA16 cDNA in its 5' region, but it is completely divergent in the 3' region. Characterization of the MTA13 mRNA as well as its genomic organization are presented. The results herein reported support the hypothesis that MTA13 and MTA16 mRNAs are encoded by the same gene.
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