First Author | Fritz JD | Year | 1993 |
Journal | Comp Biochem Physiol B | Volume | 105 |
Issue | 2 | Pages | 357-60 |
PubMed ID | 8359022 | Mgi Jnum | J:14388 |
Mgi Id | MGI:62557 | Doi | 10.1016/0305-0491(93)90241-v |
Citation | Fritz JD, et al. (1993) Characterization of a partial cDNA clone encoding porcine skeletal muscle titin: comparison with rabbit and mouse skeletal muscle titin sequences. Comp Biochem Physiol B Biochem Mol Biol 105(2):357-60 |
abstractText | 1. A cDNA fragment encoding 571 amino acid residues of porcine skeletal muscle titin was isolated from total RNA using RNA-PCR. 2. The porcine titin clone hybridized to a large RNA species (> 23 kb) in rabbit cardiac muscle, rabbit skeletal muscle and porcine skeletal muscle. 3. The porcine skeletal muscle titin clone encoded two types of 100-residue motifs and its amino acid sequence was 96% and 93% identical to the corresponding sequence of rabbit and mouse skeletal muscle titin, respectively. These results suggest that the titin sequence is highly conserved among mammalian species. |