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Publication : The peculiar journey of a selfish chromosome: mouse t haplotypes and meiotic drive.

First Author  Silver LM Year  1993
Journal  Trends Genet Volume  9
Issue  7 Pages  250-4
PubMed ID  8379001 Mgi Jnum  J:15374
Mgi Id  MGI:63498 Doi  10.1016/0168-9525(93)90090-5
Citation  Silver LM (1993) The peculiar journey of a selfish chromosome: mouse t haplotypes and meiotic drive. Trends Genet 9(7):250-4
abstractText  Mouse t haplotypes are descendents of a variant form of chromosome 17 that evolved the ability to propagate itself at the expense of the wild-type homolog from heterozygous +/t males. Although once enigmatic, these widespread selfish chromosomes have revealed many of their secrets in response to a combined assault with molecular, genetic and phylogenetic techniques. This review summarizes the current understanding of t haplotypes and their raison d'etre.
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