| First Author | Nonaka K | Year | 1993 |
| Journal | J Craniofac Genet Dev Biol | Volume | 13 |
| Issue | 3 | Pages | 202-5 |
| PubMed ID | 8227292 | Mgi Jnum | J:19701 |
| Mgi Id | MGI:67838 | Citation | Nonaka K, et al. (1993) Genetic and environmental effects on preimplantation development of mouse embryo in vitro. J Craniofac Genet Dev Biol 13(3):202-5 |
| abstractText | To examine the degree of the relative contribution of genetic and environmental effects to preimplantation development of mouse embryo in vitro, two-cell stage embryos collected from oviducts of five strains of inbred mice (DDD/Qdj, C3H/Qdj, C57BL/6J Sea, DBA/1J Sea, and BALB/C Sea) were cultivated up to the stage of expanded blastocyst for 72 hr. Both fertility and survival rates were calculated in each recipient and also in each strain. A Student-Newman-Keuls test for both rates showed a significant inter-strain difference and an analysis of variance done to estimate the relative importance of genetic and environmental effects on the preimplantation development of embryo showed a low degree of genetic determination for both rates. It was thus possible to conclude that the environmental effect played a more important role on preimplantation development of mouse embryo in vitro. |
