First Author | Schwarz H | Year | 1993 |
Journal | Gene | Volume | 134 |
Issue | 2 | Pages | 295-8 |
PubMed ID | 8262389 | Mgi Jnum | J:45110 |
Mgi Id | MGI:1101746 | Doi | 10.1016/0378-1119(93)90110-o |
Citation | Schwarz H, et al. (1993) A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family. Gene 134(2):295-8 |
abstractText | A 1.4-kb full-length cDNA was isolated from a library constructed from activated human T-cell leukemia virus type 1-transformed human T-lymphocytes. Sequence analysis identified this cDNA as a new member of the human nerve-growth-factor receptor/tumor-necrosis-factor receptor family and as the potential human homologue of the murine sequence, 4-1BB. The gene encodes three cysteine-rich motifs in the extracellular domain which are characteristic of this receptor family, a transmembrane region and a short N-terminal cytoplasmic portion which contains potential phosphorylation sites. |