| First Author | Nagasawa H | Year | 1993 |
| Journal | Lab Anim | Volume | 27 |
| Issue | 4 | Pages | 358-63 |
| PubMed ID | 8277709 | Mgi Jnum | J:15288 |
| Mgi Id | MGI:63415 | Doi | 10.1258/002367793780745570 |
| Citation | Nagasawa H, et al. (1993) Mammary tumour induction by pituitary grafting in male mice: an animal model for male breast cancer. Lab Anim 27(4):358-63 |
| abstractText | Isologous anterior pituitary grafting, 4 each, to 3-4-month-old SHN and SLN male mice resulted in an appearance of mammary tumours from 8 months of age and the incidence at 12 months reached 53.8% in each strain. All tumours were diagnosed as type B adenocarcinomas. In association with the results, normal mammary gland growth and mouse mammary tumour virus (MMTV)-gp52 antigen levels in the submaxillary glands were stimulated by the treatment in these strains. The effect of pituitary grafting was much less in GR/A male mice in which no mammary tumours appeared. |
