| First Author | Sakuma T | Year | 1994 |
| Journal | Biochim Biophys Acta | Volume | 1217 |
| Issue | 2 | Pages | 229-31 |
| PubMed ID | 8110842 | Mgi Jnum | J:17099 |
| Mgi Id | MGI:65152 | Doi | 10.1016/0167-4781(94)90043-4 |
| Citation | Sakuma T, et al. (1994) Molecular cloning and sequence analysis of hamster CYP2E1. Biochim Biophys Acta 1217(2):229-31 |
| abstractText | Two cDNA clones, pHSj31 and pHSj3, coding for CYP2E1 were isolated from a hamster liver cDNA library. The sequence analyses revealed that they encoded the same polypeptide of 493 amino acid residues (M(r) = 56,616) and differed from the length of their 3'-untranslated region. The deduced amino acid sequence of hamster CYP2E1 showed approx. 90% identities with those of the rats and mice, and approx. 80% identities with those of the rabbits, monkeys and humans. The NH2-terminal 35 deduced amino acid sequences of hamster CYP2E1 were completely identical with purified protein, ha P-450j. The Northern blot analysis showed that CYP2E1 was expressed in livers and to lesser extents in kidneys and lungs. |
