First Author | Gupta K | Year | 1994 |
Journal | Oncogene | Volume | 9 |
Issue | 6 | Pages | 1729-31 |
PubMed ID | 8183569 | Mgi Jnum | J:18777 |
Mgi Id | MGI:67012 | Citation | Gupta K, et al. (1994) The Unp proto-oncogene encodes a nuclear protein. Oncogene 9(6):1729-31 |
abstractText | The mouse Unp gene is related to TRE17, a human oncogene, but is not its mouse homolog. Unp is a ubiquitously expressed gene producing two related mRNAs. The protein product of Unp is localized in the nucleus. Expression of Unp from a highly active promoter results in tumorigenic transformation of NIH3T3 cells injected into athymic mice. Unp therefore encodes a novel nuclear oncoprotein. |