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Publication : Structural analysis of the mouse T-cell receptor Tcra V2 subfamily.

First Author  Wang K Year  1994
Journal  Immunogenetics Volume  40
Issue  2 Pages  116-22
PubMed ID  8026860 Mgi Jnum  J:19286
Mgi Id  MGI:67465 Doi  10.1007/BF00188174
Citation  Wang K, et al. (1994) Structural analysis of the mouse T-cell receptor Tcra V2 subfamily. Immunogenetics 40(2):116-22
abstractText  Cosmid clones containing T-cell receptor Tcra V2 subfamily gene segments have been isolated from a BALB/c cosmid library and subjected to DNA sequence analysis. The V gene segments in the Tcra V2 subfamily differ from each other by 3%-7% at the nucleotide level and 5%-16% at the amino acid level. T-cell receptor Tcra V2 gene segment polymorphisms have been identified in the B10.PL and PL/J mouse strains with a Tcra V2 subfamily-specific probe. These V gene segment polymorphisms may cause the differential Tcra V gene usage in induced experimental allergic encephalomyelitis between B10.PL and PL/J mice.
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