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Publication : Roles of Hox genes: what we have learnt from gain of function and loss of function mutations in the mouse.

First Author  Mark M Year  1993
Journal  C R Acad Sci III Volume  316
Issue  9 Pages  995-1008
PubMed ID  7915637 Mgi Jnum  J:15447
Mgi Id  MGI:63568 Citation  Mark M, et al. (1993) Roles of Hox genes: what we have learnt from gain of function and loss of function mutations in the mouse. C R Acad Sci III 316(9):1002-8
abstractText  Transgenic mice expressing ectopically a gene from one of the Hox complexes, and mice carrying a null mutation in a Hox gene, provide useful tools for studying the roles of this gene family during development. Here, we discuss the phenotypes of two kinds of Hox mutant mice which show that vertebrate Hox genes are functional homologues of Drosophila genes of the HOM-C complex.
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