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Publication : Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1.

First Author  Taketo M Year  1994
Journal  Genomics Volume  21
Issue  1 Pages  251-3
PubMed ID  8088797 Mgi Jnum  J:18308
Mgi Id  MGI:66308 Doi  10.1006/geno.1994.1252
Citation  Taketo M, et al. (1994) Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1. Genomics 21(1):251-3
abstractText  Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.
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