First Author | Taketo M | Year | 1994 |
Journal | Genomics | Volume | 21 |
Issue | 1 | Pages | 251-3 |
PubMed ID | 8088797 | Mgi Jnum | J:18308 |
Mgi Id | MGI:66308 | Doi | 10.1006/geno.1994.1252 |
Citation | Taketo M, et al. (1994) Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1. Genomics 21(1):251-3 |
abstractText | Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1. |