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Publication : Generation and characterization of an ordered lambda clone array for the 460-kb region surrounding the murine Xist sequence.

First Author  Rougeulle C Year  1994
Journal  Mamm Genome Volume  5
Issue  7 Pages  416-23
PubMed ID  7726900 Mgi Jnum  J:19186
Mgi Id  MGI:67381 Doi  10.1007/BF00357001
Citation  Rougeulle C, et al. (1994) Generation and characterization of an ordered lambda clone array for the 460-kb region surrounding the murine Xist sequence. Mamm Genome 5(7):416-23
abstractText  The Xist sequence has several characteristics that make it a potential candidate for the X-inactivation center. To investigate the role of Xist and adjacent sequences lying within the X-inactivation center candidate region, a 460-kb region surrounding the murine Xist sequence has been arrayed in lambda contigs with a combination of IRS-PCR-based hybridization and YAC fragmentation. The orientation of the Xist sequence in relation to the telomere and centromere of the X Chromosome (Chr) has been established with this contig and shown to be inverted compared to that in human.
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