First Author | Rougeulle C | Year | 1994 |
Journal | Mamm Genome | Volume | 5 |
Issue | 7 | Pages | 416-23 |
PubMed ID | 7726900 | Mgi Jnum | J:19186 |
Mgi Id | MGI:67381 | Doi | 10.1007/BF00357001 |
Citation | Rougeulle C, et al. (1994) Generation and characterization of an ordered lambda clone array for the 460-kb region surrounding the murine Xist sequence. Mamm Genome 5(7):416-23 |
abstractText | The Xist sequence has several characteristics that make it a potential candidate for the X-inactivation center. To investigate the role of Xist and adjacent sequences lying within the X-inactivation center candidate region, a 460-kb region surrounding the murine Xist sequence has been arrayed in lambda contigs with a combination of IRS-PCR-based hybridization and YAC fragmentation. The orientation of the Xist sequence in relation to the telomere and centromere of the X Chromosome (Chr) has been established with this contig and shown to be inverted compared to that in human. |