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Publication : The gene encoding the MOK-2 zinc-finger protein: characterization of its promoter and negative regulation by mouse Alu type-2 repetitive elements.

First Author  Arranz V Year  1994
Journal  Gene Volume  149
Issue  2 Pages  293-8
PubMed ID  7959005 Mgi Jnum  J:21624
Mgi Id  MGI:69559 Doi  10.1016/0378-1119(94)90164-3
Citation  Arranz V, et al. (1994) The gene encoding the MOK-2 zinc-finger protein: characterization of its promoter and negative regulation by mouse Alu type-2 repetitive elements. Gene 149(2):293-8
abstractText  The mouse gene MOK-2 encodes a protein with seven highly similar zinc fingers. The MOK-2 transcripts are preferentially detected in transformed cell lines, brain and testis tissues. The characterized 5'-flanking sequence differs from those of tissue-specific genes previously described. DNA sequence analysis shows that the promoter region lacks TATA and CCAAT boxes. Two short interspersed mouse genomic repeats (B2 sequences) found in this region exert a negative cis-acting effect on MOK-2 promoter activity.
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