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Publication : A transcript family from a long-range repeat cluster of the house mouse.

First Author  Weichenhan D Year  1995
Journal  Genome Volume  38
Issue  2 Pages  239-45
PubMed ID  7774798 Mgi Jnum  J:25257
Mgi Id  MGI:72982 Doi  10.1139/g95-029
Citation  Weichenhan D, et al. (1995) A transcript family from a long-range repeat cluster of the house mouse. Genome 38(2):239-45
abstractText  A family of closely related genes is a component of the polymorphic long-range repeat cluster D1Lub1 of the house mouse. Members of the gene family have diverged from one another by rearrangements and point mutations. D1Lub1 cluster have low (approximately 50) or high (> or = 500) copy numbers. In mice with high-copy clusters five or six poly(A)+ RNAs are found, while in mice with low-copy clusters only a single member of the RNA family is detected. The RNA family is synthesized in a tissue-independent manner. Each member of the RNA family is defined by a set of DNA probes. Cross hybridization with the probes reveals common 5' regions and variable remaining parts. The RNA variants are probably transcribed from different gene copies.
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