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Publication : Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis.

First Author  Skynner MJ Year  1995
Journal  Genomics Volume  25
Issue  1 Pages  207-13
PubMed ID  7774920 Mgi Jnum  J:22864
Mgi Id  MGI:70752 Doi  10.1016/0888-7543(95)80127-8
Citation  Skynner MJ, et al. (1995) Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis. Genomics 25(1):207-13
abstractText  The ky mouse mutant, kyphoscoliosis, exhibits a degenerative muscle disease resulting in chronic deformation of the spinal column. Using an interspecific backcross segregating the ky mutation, we have mapped the ky locus to a small region of mouse chromosome 9. ky is nonrecombinant with the microsatellites D9Mit24 and D9Mit169 and lies in a conserved linkage group that encompasses human chromosome 3. s-Laminin (LAMS) and the gene for dystrophin-associated glycoprotein 1 (DAG1), which map to human chromosome 3, are both recombinant with ky, ruling them out as candidates.
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