First Author | Skynner MJ | Year | 1995 |
Journal | Genomics | Volume | 25 |
Issue | 1 | Pages | 207-13 |
PubMed ID | 7774920 | Mgi Jnum | J:22864 |
Mgi Id | MGI:70752 | Doi | 10.1016/0888-7543(95)80127-8 |
Citation | Skynner MJ, et al. (1995) Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis. Genomics 25(1):207-13 |
abstractText | The ky mouse mutant, kyphoscoliosis, exhibits a degenerative muscle disease resulting in chronic deformation of the spinal column. Using an interspecific backcross segregating the ky mutation, we have mapped the ky locus to a small region of mouse chromosome 9. ky is nonrecombinant with the microsatellites D9Mit24 and D9Mit169 and lies in a conserved linkage group that encompasses human chromosome 3. s-Laminin (LAMS) and the gene for dystrophin-associated glycoprotein 1 (DAG1), which map to human chromosome 3, are both recombinant with ky, ruling them out as candidates. |