| First Author | Gecz J | Year | 1995 |
| Journal | Genomics | Volume | 26 |
| Issue | 1 | Pages | 130-3 |
| PubMed ID | 7782071 | Mgi Jnum | J:23898 |
| Mgi Id | MGI:71635 | Doi | 10.1016/0888-7543(95)80091-y |
| Citation | Gecz J, et al. (1995) Assignment of a Polycomb-like chromobox gene (CBX2) to human chromosome 17q25. Genomics 26(1):130-3 |
| abstractText | A human clone corresponding to the homologue of the murine Polycomb-like gene M33 has been used to map this gene (CBX2) to human chromosomes. Both somatic cell hybrid panels and FISH on metaphase chromosomes have been used. These techniques gave a consistent localization, at the tip of the long arm of chromosome 17 (17q25). This localization, as well as the potential role of a mammalian Polycomb-like protein, suggests a potential involvement in two different pathologies: the campomelic syndrome, an inherited disorder, and neoplastic disorders linked to allele loss already described in this region. |
