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Publication : Chromosomal localization of three mouse diacylglycerol kinase (DAGK) genes: genes sharing sequence homology to the Drosophila retinal degeneration A (rdgA) gene.

First Author  Pilz A Year  1995
Journal  Genomics Volume  26
Issue  3 Pages  599-601
PubMed ID  7607687 Mgi Jnum  J:25236
Mgi Id  MGI:72963 Doi  10.1016/0888-7543(95)80182-l
Citation  Pilz A, et al. (1995) Chromosomal localization of three mouse diacylglycerol kinase (DAGK) genes: genes sharing sequence homology to the Drosophila retinal degeneration A (rdgA) gene. Genomics 26(3):599-601
abstractText  There is growing evidence to support some form of light-activated phosphoinositide signal transduction pathway in the mammalian retina. Although this pathway plays no obvious role in mammalian phototransduction, mutations in this pathway cause retinal degenerations in Drosophila. These include the retinal degeneration A mutant, which is caused by an alteration in an eye-specific diacylglycerol kinase (DAGK) gene. In our efforts to consider genes mutated in Drosophila as candidates for mammalian eye disease, we have initially determined the map position of three DAGK genes in the mouse.
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