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Publication : Transforming growth factor alpha.

First Author  Kumar V Year  1995
Journal  Cell Biol Int Volume  19
Issue  5 Pages  373-88
PubMed ID  7640654 Mgi Jnum  J:26900
Mgi Id  MGI:74327 Doi  10.1006/cbir.1995.1083
Citation  Kumar V, et al. (1995) Transforming growth factor alpha. Cell Biol Int 19(5):373-88
abstractText  Transforming growth factor alpha (TGF alpha) is a close relative of epidermal growth factor (EGF), the first polypeptide mitogen discovered in 1962 (Cohen, 1962). TGF alpha, like EGF, exerts its effect on cells through binding to the EGF-Receptor (EGF-R). Here we review the molecular and cell biology of TGF alpha before proceeding to describe our own work on signaling molecules induced in response to activation of the EGF-R.
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