| First Author | Gobl AE | Year | 1995 |
| Journal | Cytogenet Cell Genet | Volume | 71 |
| Issue | 3 | Pages | 257-9 |
| PubMed ID | 7587389 | Mgi Jnum | J:29706 |
| Mgi Id | MGI:77231 | Doi | 10.1159/000134122 |
| Citation | Gobl AE, et al. (1995) Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-beta 3 (Plcb3), to chromosome region 19B by FISH. Cytogenet Cell Genet 71(3):257-9 |
| abstractText | A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse homologs of the human multiple endocrine neoplasia type 1 (MEN1) flanking markers proximal to the locus. We have recently shown that phospholipase C-beta 3 (PLCB3) is a candidate gene for the MEN1 syndrome. In the present investigation we used fluorescence in situ hybridization with a genomic DNA clone for mouse Plcb3, and mapped the locus to chromosome region 19B. This is in agreement with the comparative mapping of the MEN1 flanking markers in mouse. |
