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Publication : Towards unravelling the Igf2/H19 imprinted domain.

First Author  Viville S Year  1995
Journal  Bioessays Volume  17
Issue  10 Pages  835-8
PubMed ID  7487965 Mgi Jnum  J:29821
Mgi Id  MGI:77337 Doi  10.1002/bies.950171004
Citation  Viville S, et al. (1995) Towards unravelling the Igf2/H19 imprinted domain. Bioessays 17(10):835-8
abstractText  Genomic imprinting is an epigenetic marking process that confers parent-of-origin-dependent expression on certain genes. These imprinted genes are sometimes found in clusters, suggesting a possible involvement of higher order regulatory elements controlling expression and imprinting of genes organised in such clusters. In the distal chromosome 7 there are at least four imprinted genes: Mash2, Ins2, Igf2 and H19. Recent evidence suggests that imprinting and expression of at least Igf2 and H19 may be mechanistically linked.
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