First Author | Gariboldi M | Year | 1995 |
Journal | Mol Carcinog | Volume | 14 |
Issue | 2 | Pages | 71-4 |
PubMed ID | 7576101 | Mgi Jnum | J:30180 |
Mgi Id | MGI:77694 | Doi | 10.1002/mc.2940140202 |
Citation | Gariboldi M, et al. (1995) Genetic mapping and expression analysis of the murine DNA ligase I gene. Mol Carcinog 14(2):71-4 |
abstractText | We mapped the murine DNA ligase I gene (Lig1) in the mouse genome by using a mapping panel from an interspecific cross. Lig1 mapped to a centromeric part of chromosome 7, a region homologous to human chromosome 19q, where the human homologue LIG1 was localized. In addition, Lig1 expression was analyzed during the course of mouse liver-cell regeneration induced by partial hepatectomy, necrogenic doses of carbon tetrachloride, or the mitogen 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene. The results demonstrate that Lig1 is expressed in the liver during active cell proliferation. |