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Publication : Genetic susceptibility to Alzheimer disease.

First Author  Pericak-Vance MA Year  1995
Journal  Trends Genet Volume  11
Issue  12 Pages  504-8
PubMed ID  8533168 Mgi Jnum  J:42424
Mgi Id  MGI:1095708 Doi  10.1016/s0168-9525(00)89161-1
Citation  Pericak-Vance MA, et al. (1995) Genetic susceptibility to Alzheimer disease. Trends Genet 11(12):504-8
abstractText  Alzheimer disease (AD) is the leading cause of dementia in the elderly. Less than a decade ago, it was questioned as to whether or not genes were even involved in anything but rare early onset AD. Since that time, using a variety of genetic epidemiological and molecular biological techniques, four loci have been identified that play a role in the genetic susceptibility of AD. AD presents as a prototype of the power of genetic techniques in defining the etiology of a complex disease.
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