| First Author | Okazaki K | Year | 1995 |
| Journal | Peptides | Volume | 16 |
| Issue | 7 | Pages | 1295-9 |
| PubMed ID | 8545254 | Mgi Jnum | J:29992 |
| Mgi Id | MGI:77514 | Doi | 10.1016/0196-9781(95)02018-r |
| Citation | Okazaki K, et al. (1995) Characterization of murine PACAP mRNA. Peptides 16(7):1295-9 |
| abstractText | A murine PACAP precursor cDNA was isolated by screening a brain cDNA library. The amino acid sequence of the precursor was highly similar (from 81% to 93% similarity) to its rat, human, and ovine counterparts. The primary structure of murine PACAP is identical with those from sheep, humans, and rats, indicating that the mature PACAP is well conserved among mammals. Northern blot analysis revealed that the approximately 2.4 kb transcript for the PACAP precursor is expressed in murine brain. The verification that murine PACAP is identical to its human counterpart provides a rationale for physiological and pathophysiological studies of PACAP in mice. |
