| First Author | Péterfy M | Year | 1995 |
| Journal | Somat Cell Mol Genet | Volume | 21 |
| Issue | 5 | Pages | 345-9 |
| PubMed ID | 8619131 | Mgi Jnum | J:31743 |
| Mgi Id | MGI:79674 | Doi | 10.1007/BF02257469 |
| Citation | Peterfy M, et al. (1995) Localization of the mouse lissencephaly-1 gene to mouse chromosome 11B3, in close proximity to D11Mit65. Somat Cell Mol Genet 21(5):345-9 |
| abstractText | Lissencephaly is a human brain malformation manifested by a smooth cerebral surface and severe mental retardation. Some of the patients have been shown to have deletions in chromosome 17p13.3, and recently, LIS-1 has been proposed to be the disease-associated gene. We have now mapped the mouse homolog of LIS-1 to mouse chromosome 11B3 by using fluorescence in situ hybridization to metaphase chromosomes. The analysis of yeast artificial chromosome clones placed Lis-1 in close proximity to the microsatellite marker D11Mit65. |