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Publication : Chromosomal localization of murine and human oligodendrocyte-specific protein genes.

First Author  Bronstein JM Year  1996
Journal  Genomics Volume  34
Issue  2 Pages  255-7
PubMed ID  8661061 Mgi Jnum  J:33372
Mgi Id  MGI:80853 Doi  10.1006/geno.1996.0278
Citation  Bronstein JM, et al. (1996) Chromosomal localization of murine and human oligodendrocyte-specific protein genes. Genomics 34(2):255-7
abstractText  Oligodendrocyte-specific protein (OSP) is a recently described protein present only in myelin of the central nervous system, Several inherited disorders of myelin are caused by mutations in myelin genes but the etiology of many remain unknown, We mapped the location of the mouse OSP gene to the proximal region of chromosome 3 using two sets of multilocus crosses and to human chromosome 3 using somatic cell hybrids, Fine mapping with fluorescence in situ hybridization placed the OSP gene at human chromosome 3q26.2-q26.3. To date, there are no known inherited neurological disorders that localize to these regions. (C) 1996 Academic Press, Inc.
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