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Publication : Characterization of the 3' UTR sequence encoded by the AQP-1 gene in human retinal pigment epithelium.

First Author  Ruiz A Year  1996
Journal  Biochim Biophys Acta Volume  1282
Issue  2 Pages  174-8
PubMed ID  8703970 Mgi Jnum  J:34463
Mgi Id  MGI:81920 Doi  10.1016/0005-2736(96)00076-4
Citation  Ruiz A, et al. (1996) Characterization of the 3' UTR sequence encoded by the AQP-1 gene in human retinal pigment epithelium. Biochim Biophys Acta 1282(2):174-8
abstractText  The complete 3' UTR sequence encoded by the human aquaporin-1 gene is reported. The sequence encompassed by two cDNA clones showed, 33 nucleotides of 5' UTR sequence, a coding sequence of 807 nucleotides and 1886 nucleotides corresponding to the complete 3' UTR sequence. High similarity with 3' UTR sequences from rat and mouse counterparts was found. Northern blot analysis of several human tissues revealed a 2.8 kbp transcript. These data confirm the existence of water channels in the human retinal pigment epithelium.
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