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Publication : Differential expression of LIM-homeodomain genes in the embryonic murine brain.

First Author  Matsumoto K Year  1996
Journal  Neurosci Lett Volume  211
Issue  3 Pages  147-50
PubMed ID  8817562 Mgi Jnum  J:34662
Mgi Id  MGI:82116 Doi  10.1016/0304-3940(96)12749-x
Citation  Matsumoto K, et al. (1996) Differential expression of LIM-homeodomain genes in the embryonic murine brain. Neurosci Lett 211(3):147-50
abstractText  Homeobox-containing genes are associated with the control of various stages in embryogenesis. LIM-homeodomain genes have been implicated in the control of differentiation of specific cell types in both neuronal and non-neuronal tissues, yet there have been few studies comparing the expression domains of these genes in the developing brain of a single species. In the present study, we isolated murine LIM-homeodomain genes (LH-2, lim-1, and L3) by reverse transcription-polymerase chain reaction (RT-PCR) method and investigated their expression domains in the embryonic brain by in situ hybridization analysis. These mRNAs showed mutually exclusive expression patterns suggesting that these factors may be involved in region-specific differentiation in the developing brain.
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