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Publication : Mapping TNNC1, the gene that encodes cardiac troponin I in the human and the mouse.

First Author  Bermingham N Year  1995
Journal  Genomics Volume  30
Issue  3 Pages  620-2
PubMed ID  8825654 Mgi Jnum  J:30586
Mgi Id  MGI:78085 Doi  10.1006/geno.1995.1288
Citation  Bermingham N, et al. (1995) Mapping TNNC1, the gene that encodes cardiac troponin I in the human and the mouse. Genomics 30(3):620-2
abstractText  We have mapped the TNNC1 gene, whose protein product is the cardiac TnI protein. TnI is one of the proteins that makes up the troponin complex, which mediates the response of muscle to calcium ions. The human TNNC1 locus had been assigned to a large region of chromosome 19, and we have refined the mapping position to the distal end of the chromosome by amplification of DNAs from a chromosome 19 mapping panel. We have also mapped the mouse Tnnc1 locus, by following the segregation of an intron sequence through DNAs from the European Interspecific Backcross. Tnnc1 maps close to the centromere on mouse chromosome 7. (C) 1995 Academic Press, Inc.
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