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Publication : New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13.

First Author  Xu HP Year  1996
Journal  Mamm Genome Volume  7
Issue  1 Pages  16-9
PubMed ID  8903722 Mgi Jnum  J:30838
Mgi Id  MGI:78403 Doi  10.1007/s003359900005
Citation  Xu HP, et al. (1996) New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13. Mamm Genome 7(1):16-9
abstractText  We have used a Mus domesticus/-Mus spretus congenic animal that was selected for retention of Mus spretus DNA around the pearl locus to create a highly polymorphic region suitable for screening new markers. Representation difference analysis (RDA) was performed with either DNA from the congenic animal or C57BL/6J as the driver for subtraction. Four clones were identified, characterized, and converted to PCR-based polymorphic markers. Three of the foul markers equally subdivide a 10-cM interval containing the pearl locus, with the fourth located centromeric to it. These markers have been placed on the mouse genetic map by use of an interspecific backcross panel between Mus domesticus (C57BL/6J) and Mus spretus generated by The Jackson Laboratory.
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