| First Author | Lima HC | Year | 1996 |
| Journal | Infect Immun | Volume | 64 |
| Issue | 12 | Pages | 5442-5 |
| PubMed ID | 8945606 | Mgi Jnum | J:36858 |
| Mgi Id | MGI:84271 | Doi | 10.1128/iai.64.12.5442-5445.1996 |
| Citation | Lima HC, et al. (1996) Effects of sand fly vector saliva on development of cutaneous lesions and the immune response to Leishmania braziliensis in BALB/c mice. Infect Immun 64(12):5442-5 |
| abstractText | The saliva of the sand fly vector of leishmaniasis significantly enhanced infection with doses of >10(4) Leishmania braziliensis parasites in BALB/c mice. With a dose of 10(7) L. braziliensis parasites, 60 to 70% of the mice developed lifetime infections. Mice infected with L. braziliensis plus saliva produced two- to threefold more interleukin-4 than did mice infected with L. braziliensis alone. Treatment with a neutralizing anti-interleukin-4 antibody abrogated the effects of the saliva. |
