| First Author | Abdul Motaleb M | Year | 1996 |
| Journal | J Biochem | Volume | 120 |
| Issue | 4 | Pages | 797-802 |
| PubMed ID | 8947844 | Mgi Jnum | J:36519 |
| Mgi Id | MGI:83948 | Doi | 10.1093/oxfordjournals.jbchem.a021482 |
| Citation | Abdul Motaleb M, et al. (1996) Structural organization of the rae28 gene, a putative murine homologue of the Drosophila polyhomeotic gene. J Biochem 120(4):797-802 |
| abstractText | A putative murine homologue of the Drosophila polyhomeotic gene, named rae28, has been isolated from a genomic library of 129/SV mouse and its structural organization has been analyzed, rae28 is a single gene of approximately 22 kb long and consists of 15 exons. Its 5'-flanking region lacks typical transcriptional regulatory sequences, such as TATA and CCAAT boxes, but contains GC-rich sequences and seven putative binding sites for a transcription factor, Sp1. One major transcription start point has been determined. The overall exon-intron organization suggested that three different Rae28 mRNAs are generated through alternative splicing, Furthermore, the rae28 gene has been located on the R-positive F3 band of mouse chromosome 6 by the direct R-banding fluorescence in situ hybridization methods. |
