| First Author | Schupp IW | Year | 1997 |
| Journal | Immunogenetics | Volume | 45 |
| Issue | 3 | Pages | 180-7 |
| PubMed ID | 8995184 | Mgi Jnum | J:38734 |
| Mgi Id | MGI:86116 | Doi | 10.1007/s002510050187 |
| Citation | Schupp IW, et al. (1997) A yeast artificial chromosome contig spanning the mouse immunoglobulin kappa light chain locus. Immunogenetics 45(3):180-7 |
| abstractText | A single contig spanning the entire mouse immunoglobulin kappa light chain (Igk) locus on chromosome 6 has been established using yeast and bacterial artificial chromosome clones. Detailed mapping of the Igk locus indicates that a member of the Igk-V2 gene family, located about 3.5 megabases upstream of the Igk-J-C complex, is the most distal functional Igk-V gene. Sequence analyses of Igk-V genes and anonymous DNA segments provide indications for internal duplications at the 5' end of the Igk-V locus and identify the likely origin of Igk-V orphon gene clusters located elsewhere in the mouse genome. |
