First Author | Byrd PJ | Year | 1997 |
Journal | Genome Res | Volume | 7 |
Issue | 1 | Pages | 71-5 |
PubMed ID | 9037604 | Mgi Jnum | J:38757 |
Mgi Id | MGI:86143 | Doi | 10.1101/gr.7.1.71 |
Citation | Byrd PJ, et al. (1997) Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23 [letter]. Genome Res 7(1):71-5 |
abstractText | We have localized the human homolog of the rabbit vasopressin-activated calcium-mobilizing receptor VACM-1 to a region close to the gene for ataxia telangiectasia ATM on chromosome 11q22-23. We have determined the complete amino acid sequence of the human Hs-VACM-1 protein, which is 780 amino acids long. The human and rabbit sequences are highly conserved, differing at only seven amino acids. Northern analysis of the human gene showed expression in a wide range of human tissues. The Hs-VACM-1 gene has homology with the Caenorhabditis elegans gene Ce-cul-5, a member of a family of cullin genes that are involved in cell cycle regulation and that might, when mutated, contribute to tumor progression. |