| First Author | Marlow SA | Year | 1997 |
| Journal | J Anat | Volume | 190 ( Pt 2) |
| Pages | 223-7 | PubMed ID | 9061445 |
| Mgi Jnum | J:39101 | Mgi Id | MGI:86482 |
| Doi | 10.1046/j.1469-7580.1997.19020223.x | Citation | Marlow SA, et al. (1997) Investigation of the influence of the Mm musculus MyoD1 allele on the efficiency of skeletal muscle regeneration. J Anat 190(Pt 2):223-7 |
| abstractText | MyoD1 alleles distinguish between the Mm musculus and Mm domesticus subspecies of Mus musculus. SJL/J mice, which belong to the Mm musculus subspecies, are able to regenerate skeletal muscle more efficiently than BALB/c mice which possess the Mm domesticus MyoD1 allele. Hence the possibility that regeneration responses are due to species-specific genetic differences including MyoD1 was investigated in this study. Quantitative morphometric analysis following muscle crush injury of 2 Mm musculus strains, MBK and MGL, has indicated that regeneration phenotype is not species-specific and may not be directly related to MyoD1 alleles. These results contrast with prior investigations conducted in SJL/J and BALB/c mice, and indicate that other genes may have a direct influence on skeletal muscle regeneration. |
