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Publication : The human erythroid-specific transcription factor EKLF localizes to chromosome 19p13.12-p13.13.

First Author  van Ree JH Year  1997
Journal  Genomics Volume  39
Issue  3 Pages  393-5
PubMed ID  9119377 Mgi Jnum  J:38416
Mgi Id  MGI:85786 Doi  10.1006/geno.1996.4472
Citation  van Ree JH, et al. (1997) The human erythroid-specific transcription factor EKLF localizes to chromosome 19p13.12-p13.13. Genomics 39(3):393-5
abstractText  Erythroid Kruppel-like factor (EKLF) is a trans-acting factor that binds specifically to the beta-globin promoter CACCC box. EKLF is essential for adult erythroid development in mice. We have cloned and sequenced a cDNA encoding the human homologue of this gene, which shares 69% identity with the mEKLF protein. The expression of hEKLF is restricted to fetal liver and adult bone marrow. The genomic locus of hEKLF was mapped to chromosomal band 19p13.12-p13.13, using fluorescence in situ hybridization.
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