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Publication : Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system.

First Author  Frisén J Year  1997
Journal  Cell Tissue Res Volume  290
Issue  2 Pages  209-15
PubMed ID  9321682 Mgi Jnum  J:43921
Mgi Id  MGI:1099143 Doi  10.1007/s004410050925
Citation  Frisen J, et al. (1997) Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system. Cell Tissue Res 290(2):209-15
abstractText  The Eph family of tyrosine protein kinase receptors and their cognate ligands, a family of membrane-bound molecules known as ephrins, have been implicated in diverse biological processes, such as axon guidance, the formation of topographic neural projections, axon fasciculation, the regionalization of the central nervous system, and cell migration. The recent generation of mutant mice lacking some of these receptors has made possible the dissection of the role that these molecules play in the development of the mammalian nervous system.
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