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Publication : Molecular cloning of cyclic nucleotide-gated cation channel subunits from rat pineal gland.

First Author  Sautter A Year  1997
Journal  Brain Res Mol Brain Res Volume  48
Issue  1 Pages  171-5
PubMed ID  9379842 Mgi Jnum  J:42142
Mgi Id  MGI:1095228 Doi  10.1016/s0169-328x(97)00155-1
Citation  Sautter A, et al. (1997) Molecular cloning of cyclic nucleotide-gated cation channel subunits from rat pineal gland. Brain Res Mol Brain Res 48(1):171-5
abstractText  We have investigated the subunit composition and the molecular structure of the CNG channel expressed in rat pineal gland. Three types of subunits have been cloned: an alpha-subunit (CNG1), two beta-subunit splice variants (rCNG4.1 and rCNG4.2) and a hydrophilic glutamic acid-rich protein (rGARP). In situ hybridization with sections of rat brain revealed the co-expression of CNG1, CNG4 and GARP in pinealocytes. In addition, CNG4-specific transcripts were detected in the arcuate, periventricular and supraoptic nuclei of the hypothalamus.
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