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Publication : Rab17 and rab18, small GTPases with specificity for polarized epithelial cells: genetic mapping in the mouse.

First Author  McMurtrie EB Year  1997
Journal  Genomics Volume  45
Issue  3 Pages  623-5
PubMed ID  9367688 Mgi Jnum  J:38314
Mgi Id  MGI:85690 Doi  10.1006/geno.1997.4959
Citation  McMurtrie EB, et al. (1997) Rab17 and rab18, small GTPases with specificity for polarized epithelial cells: genetic mapping in the mouse. Genomics 45(3):623-5
abstractText  The Rab subfamily of small GTPases plays an important role in the regulation of membrane traffic in eukaryotic cells. While most Rab proteins are equally expressed in polarized and nonpolarized cells, Rab17 and Rab18 show epithelial cell specificity. Here we report the genetic mapping of Rab17 and Rab18 on mouse chromosomes 1 and 18, respectively. We also discuss some implications of Rab17 and Rab18 mapping, including their candidacy for the mouse mutations ln (leaden), Tw (twirler), and ax (ataxia). Copyright 1997 Academic Press.
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