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Publication : Isolation and characterization of 5'-regulatory region of mouse activin beta A subunit gene.

First Author  Yoshida E Year  1998
Journal  Biochem Mol Biol Int Volume  44
Issue  2 Pages  325-32
PubMed ID  9530515 Mgi Jnum  J:46735
Mgi Id  MGI:1202013 Doi  10.1080/15216549800201342
Citation  Yoshida E, et al. (1998) Isolation and characterization of 5'-regulatory region of mouse activin beta A subunit gene. Biochem Mol Biol Int 44(2):325-32
abstractText  We isolated genomic clones that contain the 5'-flanking region of the mouse activin beta A subunit gene. The nucleotide sequence determination of the 5'-flanking region of the gene and the comparison of that with the reported mouse cDNA structure identified the putative 5' regulatory region, a novel first exon and a part of the first intron of the gene within this region. The putative 5' regulatory region of the mouse activin beta A subunit gene directed the expression of CAT gene in transfected HT1080 cells. Successive deletions of this region demonstrated a 400-bp region that exerts a strong positive effect on promoter activity of the mouse activin beta A subunit gene.
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