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Publication : Expression of the axon growth-related neural adhesion molecule TAG-1/axonin-1 in the adult mouse brain.

First Author  Wolfer DP Year  1998
Journal  Anat Embryol (Berl) Volume  197
Issue  3 Pages  177-85
PubMed ID  9543336 Mgi Jnum  J:46727
Mgi Id  MGI:1202005 Doi  10.1007/s004290050129
Citation  Wolfer DP, et al. (1998) Expression of the axon growth-related neural adhesion molecule TAG-1/axonin-1 in the adult mouse brain. Anat Embryol (Berl) 197(3):177-85
abstractText  TAG-1/axonin-1 is a neuronal cell adhesion molecule of the immunoglobulin superfamily. It is predominantly expressed during neural development and has been reported to be involved in axonal growth and pathfinding. Here, the expression of TAG-1/axonin-1 was investigated anatomically in the adult mouse brain by in situ hybridization using digoxigenin-labeled cRNA probes. Low levels of TAG-1/axonin-1 could be detected in cerebellar granule cells, in tufted and mitral cells of the olfactory bulb, and in pyramidal cells of area CA1 and CA3 of the hippocampus. We suspect that the expression of TAG-1/axonin-1 in these structures of the adult brain may serve neural plasticity.
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