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Publication : Cloning and sequencing of the bovine STAT5A cDNA reveals significant sequence divergence with ovine.

First Author  Schröder P Year  1998
Journal  Biochim Biophys Acta Volume  1398
Issue  2 Pages  99-105
PubMed ID  9689910 Mgi Jnum  J:48462
Mgi Id  MGI:1270027 Doi  10.1016/s0167-4781(98)00054-2
Citation  Schroder P, et al. (1998) Cloning and sequencing of the bovine STAT5A cDNA reveals significant sequence divergence with ovine. Biochim Biophys Acta 1398(2):99-105
abstractText  The transcription factors STAT5 mediates prolactin signals in mammary epithelial cells. The cDNA of bovine STAT5A was cloned, sequenced and compared to other species. The encoded protein proves to be > 95% homologous to other mammals. We show that the STAT5A mRNA of the closely related ovine species contains an extended (by 130 nt) 5'-untranslated region, being encoded by an extra-exon, and accounts, possibly, for improved translation efficiency.
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