| First Author | Wagenfeld A | Year | 1998 |
| Journal | Biochem Biophys Res Commun | Volume | 251 |
| Issue | 2 | Pages | 545-9 |
| PubMed ID | 9792810 | Mgi Jnum | J:50496 |
| Mgi Id | MGI:1306745 | Doi | 10.1006/bbrc.1998.9512 |
| Citation | Wagenfeld A, et al. (1998) Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization. Biochem Biophys Res Commun 251(2):545-9 |
| abstractText | Epididymal fluid from rats rendered infertile by oral administration of ornidazole contains a protein CAP1 (contraception-associated protein 1) that is absent from epididymal fluid, but present on epididymal sperm, from fertile vehicle-treated rats. The gene for CAP1 has been isolated from a rat testis cDNA library and its expression investigated in different tissues. The deduced protein sequence of CAP1 contains 189 amino-acid residues and database searches revealed a high degree of homology (83-95%) with human and mouse DJ-1 at the nucleotide and amino acid levels. Northern blot hybridisation from different rat tissues indicated that CAP1 is encoded by a 1.6-kilobase RNA transcript and seems to be ubiquitiously expressed in the rat with a high level of expression in the testis. Copyright 1998 Academic Press. |
