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Publication : Inhibition of polyposis in the small intestine of BALB/c mice by intestinal bacteria.

First Author  Ozaki A Year  1998
Journal  Cancer Lett Volume  131
Issue  2 Pages  153-6
PubMed ID  9851247 Mgi Jnum  J:51491
Mgi Id  MGI:1316820 Doi  10.1016/s0304-3835(98)00126-8
Citation  Ozaki A, et al. (1998) Inhibition of polyposis in the small intestine of BALB/c mice by intestinal bacteria. Cancer Lett 131(2):153-6
abstractText  The incidence of polyposis and the number of polyps per mouse were significantly lower in conventionalized (CVz) mice than in germ-free (GF) mice. There was no significant difference in the average number of polyps between GF and gnotobiotic (GB) mice monoassociated with the various strains of intestinal bacteria. However, the incidence of polyposis and the number of polyps per mouse were significantly lower for mice associated with either chloroform-resistant bacteria (CRB) or fusiform bacteria (FB) than for GF mice. This study demonstrated that polyposis was suppressed by FB and CRB in the small intestine of BALB/c mice.
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