| First Author | Hobden JA | Year | 1999 |
| Journal | Infect Immun | Volume | 67 |
| Issue | 2 | Pages | 972-5 |
| PubMed ID | 9916118 | Mgi Jnum | J:52409 |
| Mgi Id | MGI:1329255 | Doi | 10.1128/iai.67.2.972-975.1999 |
| Citation | Hobden JA, et al. (1999) Pseudomonas aeruginosa keratitis in knockout mice deficient in intercellular adhesion molecule 1. Infect Immun 67(2):972-5 |
| abstractText | In this study, the role of intercellular adhesion molecule 1 (ICAM-1) in the pathogenesis of Pseudomonas aeruginosa keratitis was examined by using inbred ICAM-1-deficient knockout mice. These mice had significantly less (P </= 0.02) ocular disease than wild-type mice, suggesting that ICAM-1 contributes to a more severe disease response following P. aeruginosa infection. |
