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Publication : Testis-brain RNA-binding protein (Translin) is primarily expressed in neurons of the mouse brain.

First Author  Wu XQ Year  1999
Journal  Brain Res Volume  819
Issue  1-2 Pages  174-8
PubMed ID  10082876 Mgi Jnum  J:52832
Mgi Id  MGI:1330491 Doi  10.1016/s0006-8993(98)01322-5
Citation  Wu XQ, et al. (1999) Testis-brain RNA-binding protein (Translin) is primarily expressed in neurons of the mouse brain. Brain Res 819(1-2):174-8
abstractText  The subcellular location(s) of the DNA- and RNA-binding protein, Testis-Brain RNA-Binding Protein (TB-RBP)/Translin in mouse brain has been determined in paraffin sections by immunocytochemistry with an affinity purified antibody to mouse recombinant TB-RBP. Nuclear staining was frequently seen in neurons throughout the brain, but no TB-RBP/Translin was detected in many of the neurons in superficial layers of the cerebral cortex and in some cells of the cerebellum. Cytoplasmic staining extending into the dendrites was seen in large neurons such as pyramidal neurons in Layer 5 of the cortex and magnocellular neurons of the hypothalamus or the brainstem raphe. Copyright 1999 Elsevier Science B.V.
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